Table 3.

Echocardiographic analyses

	WT + Ad.GFP	WT + Ad.asNCX1
IVSd, mm	1.31 ± 0.19	1.13 ± 0.12
LVIDd, mm	3.09 ± 0.53	2.96 ± 0.31
LVPWd, mm	1.29 ± 0.19	1.33 ± 0.19
IVSs, mm	1.96 ± 0.40	1.94 ± 0.15
LVIDs, mm	1.41 ± 0.03	0.99 ± 0.30
LVPWs, mm	2.00 ± 0.28	2.19 ± 0.06*
%FS	54.8 ± 2.4	67 ± 7.4†
HR, beats/min	535 ± 25	559 ± 18
	Akita + Ad.GFP	Akita + Ad.asNCX1
IVSd ,mm	0.86 ± 0.09	0.77 ± 0.07
LVIDd, mm	2.78 ± 0.15	3.48 ± 0.29†
LVPWd, mm	0.97 ± 0.09	0.90 ± 0.04
IVSs, mm	1.50 ± 0.09	1.22 ± 0.14*
LVIDs, mm	1.16 ± 0.07	2.31 ± 0.32‡
LVPWs, mm	1.75 ± 0.03	1.35 ± 0.12‡
%FS	58.2 ± 4.4	33.8 ± 4.9‡
HR, beats/min	528 ± 30	541 ± 32

Values are means ± SD. Seven days postinjection echocardiography was performed. WT or Akita mice received gene transfer of Ad.GFP or Ad.asNCX1. IVSd, intraventricular septum in diastole; LVIDd and LVIDs, left ventricular internal diameter at diastole and systole ; LVPWd and LVPWs, left ventricle posterior wall diastole and systole.

^*P < 0.05;

^†P < 0.01;

^‡P < 0.001.