Fig. 1.
Starting structure for the simulation of the Arp2/3 complex branch junction. The top portion shows three views with protein subunits in surface representation and with mother (M1 to M13) and daughter filaments (D1 to D11) colored grey. Arp2/3 complex subunits are colored and labeled using a common coloring scheme expect for Arp2 in black. The pointed ends of the actin filaments are at subunits M1 and D1. The bottom portion are close up views of the active Arp2/3 complex with labels. Each view is rotated 90°. Note that ARPC4 (dark blue) is only scarcely visible as it is mostly buried at the Arp2/3—actin interface. Subunit M8 is removed in the bottom center panel to enhance viewing of the Arp2/3 complex.