Fig. 18.

Novel theranostic agent. A – schematic of nanoparticles containing a ~70 nm Au nanoshell with a silica shell doped with superparamagnetic iron oxide and ICG and surface-decorated with anti-HER2 antibodies for targeting. B – magnetic resonance imaging of the nanoparticles in vitro (no scale bar provided). C – photothermal ablation capabilities of the theranostic system demonstrated in vitro. D – fluorescence visualization of the nanoparticles after targeted uptake into OVCAR3 cells. Reproduced from Chen, et al.³⁸