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. 2012 Apr;165(8):2450–2461. doi: 10.1111/j.1476-5381.2011.01410.x

Figure 2.

Figure 2

Δ8-THCV pretreatment decreases liver I/R injury. (A and B) Serum transaminase ALT (A) and AST (B) levels in sham-operated mice treated with vehicle (veh) or Δ8-THCV (n= 5 per group) or in mice exposed to 1 h of hepatic ischaemia followed by 2h (I + 2h R) or 6 h (I + 6h R) of reperfusion pretreated with vehicle, Δ8-THCV (3 or 10 mg·kg−1) or SR144528 (SR2, 3 mg·kg−1), SR141716A (SR1, 3 and 10 mg·kg−1) and 10 mg·kg−1Δ8-THCV in combination with SR1 or SR2 (n= 6–10 per group). *P < 0.05 versus vehicle; #P < 0.05 versus corresponding mice exposed to I/R; $P < 0.05 versus corresponding mice exposed to I/R and pretreated with 10 mg·kg−1Δ8-THCV.