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. 2012 Apr;165(8):2620–2634. doi: 10.1111/j.1476-5381.2011.01621.x

Figure 2.

Figure 2

Mean (±SEM) number of vomiting episodes elicited by 20 mg·kg−1 cisplatin (Panel A) or 40 mg·kg−1 cisplatin (Panel B) by shrews pretreated with saline (SAL; right-hand sections) or WAY100135 (10 mg·kg−1, i.p.; left-hand sections) prior to the second pretreatment of vehicle (VEH), 5 mg·kg−1 CBD or 10 mg·kg−1 CBD. *P < 0.05, significant difference between other groups. The number of shrews in each group is indicated in parentheses. The M : F ratio within each treatment group for 20 mg·kg−1 cisplatin treated shrews in Panel A is: saline-vehicle (4:4), saline-5 CBD (6:6), saline-10 CBD (5:3), WAY100135-vehicle (5:5), WAY100135-5 CBD (4:3), WAY100135-10 CBD (3:5). For Panel B the M : F ratio is: saline-vehicle (3:2), saline-5 CBD (2:3), saline-10 CBD (3:3), WAY100135-vehicle (3:3), WAY100135-5 CBD (2:2) and WAY100135-10 CBD (2:3).