Effects of bilobetin on lipid contents of RQ (A–D) and liver (E–H) in rats. Nor, standard diet; HFD, high-fat diet; B14, HFD + 14 day bilobetin treatment; B4, HFD + 4 day bilobetin treatment; B14H, B14 rats treated with PKA inhibitor (H89). B4M, B4 rats treated with PPARα inhibitor (MK886); B4H, B4 rats treated with H89. Data are means ± SEM. n= 6. aP < 0.01 versus HFD group; cP < 0.01 versus B14 group; eP < 0.01 versus B4 group (anova).