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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Mol Cell Cardiol. 2012 Jul 13;53(3):437–445. doi: 10.1016/j.yjmcc.2012.07.001

Figure 4. Gain of function KATP transgene is mainly expressed in atrial tissue.

Figure 4

(A) Confocal images of two 9.5 dpc WT (control) littermate embryos (upper two images) and two 9.5 Line 4 littermate embryos hearts (lower 2 images). Note prominent GFP fluorescence in Line 4 transgenic mice throughout the hearts. A=atrium, V=ventricle, O=outflow. Sizing bar indicates 1 mm. (B) Z-sectioning (with depth information in the right upper corner of each image) confocal images of the heart from 9.5 dpc Line 4 embryo (right lower embryo in A). A=atrium, V=ventricle, O=outflow. Sizing bar indicates 0.2 mm. (C) Confocal images of two 12.5 dpc WT (control) littermate embryonic hearts (left 2 images) and two 12.5 Line 4 littermate embryonic hearts (right 2 images). Sizing bar indicates 1 mm.