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. 2012 Aug 20;7(8):e43216. doi: 10.1371/journal.pone.0043216

Table 1. Number of cows, average ± standard deviation of anti-F. hepatica antibody levels before treatment and 305-day milk production in the lactation before treatment and distribution of breed, parity and year quarter of treatment in the 2 treatment groups.

Parameter Closantel Placebo
N° of cows 208 194
Anti-F. hepatica antibody level (ODR) 0.36±0.26 0.40±0.27
305-day milk production (kg) 9,012±1,661 9,059±1,742
Breed:
Holstein Friesian 45.3 43.0
Dutch Friesian 6.5 5.2
Parity (%):
1st 11.2 10.5
2nd 16.7 13.7
≥3rd 23.9 24.1
Year quarter:
Jan–Mar 12.4 11.9
Apr–Jun 5.2 4.7
Jul–Sep 16.9 15.7
Oct–Dec 17.2 15.9