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. 2012 Aug 20;7(8):e42729. doi: 10.1371/journal.pone.0042729

Table 1. Potential advantages and pitfalls of intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT) compared to 3-dimentional conformal radiotherapy (3-D CRT).

IMRT, IGRT 3-D CRT
Advantages: Sparing of normal organs because of rapid dose fall No sparing
Tumor dose escalation possible because of different dose levels within the target volume No dose escalation
Visualization of tumor shrinkage feasible for IGRT allowing re-planning during radiotherapy No visualization
Pitfalls: Marginal miss if tumor not properly contoured leading to local recurrences. Unlikely