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. 2012 Aug 20;7(8):e43023. doi: 10.1371/journal.pone.0043023

Figure 1. The strategy of developing NAAA inhibitors.

Figure 1

A–C, the chemical structures of classic NAAA inhibitors including PEA (A), CCP (B), and (S)-OOPP (C); (D) SAR study of 1-Pentadecanyl-carbonyl pyrrolidine; (E) Dose-dependent inhibition of 1-Pentadecanyl-carbonyl pyrrolidine on NAAA activity.