Table 1. Baseline characteristics of all 140 patients.
All patients (n = 140) | ALT ≤2×ULN (n = 56) | ALT >2×ULN (n = 84) | p value* | |
Age | 32.7 (16.6–60.1) | 32.6 (16.6–55.0) | 32.5 (18.0–60.1) | 0.309 |
Number of male patients | 91 (65.0%) | 40 (71.4%) | 51 (60.7%) | 0.193 |
Albumin (U/L) | 46 (37–54) | 47 (39–52) | 45 (37–54) | 0.152 |
Bilirubin (umol/L) | 10 (3–31) | 9.5 (4–31) | 10.5 (3–30) | 0.088 |
ALT (U/L) | 67.5 (14–175) | 38 (14–60) | 89 (46–175) | <0.001 |
HBV DNA (log IU/mL) | 7.96 (4.41–12.4) | 8.14 (4.83–11.9) | 7.72 (4.41–12.4) | 0.113 |
HBsAg (IU/mL) | 17,680 (62–319,800) | 52,535 (257–319,800) | 9,362 (62–217,200) | <0.001 |
All continuous values expressed in median (range).
ALT, alanine aminotransferase; ULN, upper limit of normal; HBsAg, hepatitis B surface antigen.
ALT upper limit of normal: 30 U/L for men, 19 U/L for women.
Comparison was between patients with ALT ≤2×ULN and ALT >2×ULN.