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. 2012 Aug 20;7(8):e43087. doi: 10.1371/journal.pone.0043087

Table 1. Baseline characteristics of all 140 patients.

All patients (n = 140) ALT ≤2×ULN (n = 56) ALT >2×ULN (n = 84) p value*
Age 32.7 (16.6–60.1) 32.6 (16.6–55.0) 32.5 (18.0–60.1) 0.309
Number of male patients 91 (65.0%) 40 (71.4%) 51 (60.7%) 0.193
Albumin (U/L) 46 (37–54) 47 (39–52) 45 (37–54) 0.152
Bilirubin (umol/L) 10 (3–31) 9.5 (4–31) 10.5 (3–30) 0.088
ALT (U/L) 67.5 (14–175) 38 (14–60) 89 (46–175) <0.001
HBV DNA (log IU/mL) 7.96 (4.41–12.4) 8.14 (4.83–11.9) 7.72 (4.41–12.4) 0.113
HBsAg (IU/mL) 17,680 (62–319,800) 52,535 (257–319,800) 9,362 (62–217,200) <0.001

All continuous values expressed in median (range).

ALT, alanine aminotransferase; ULN, upper limit of normal; HBsAg, hepatitis B surface antigen.

ALT upper limit of normal: 30 U/L for men, 19 U/L for women.

*

Comparison was between patients with ALT ≤2×ULN and ALT >2×ULN.