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CONDITIONAL ANALYSIS OF CHRNA3/5 AND IREB2
| Gene | SNP | Conditioned on | OR (95% CI) | P Value |
| IREB2 | rs13180 | rs8034191 | 0.89 (0.67–1.19) | 0.45 |
| CHRNA3/5 | rs8034191 | rs13180 | 1.75 (1.31–2.32) | 1.4 × 10−4 |
Definition of abbreviations: CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism.
Logistic regression was performed in PLINK, using conditional analysis with the conditioned SNP included as a covariate. Age, sex, and pack-years comprised additional covariates.
