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. 2012 Aug;47(2):234–244. doi: 10.1165/rcmb.2012-0026OC

Figure 5.

Figure 5.

Transcript levels of candidate genes that differed between the C57BL/10J and C57BLKS/J murine strains after chlorine exposure. Female mice were exposed to filtered air (control, 0 hours), or to chlorine (45 ppm) for 6 or 12 hours, lung mRNA was isolated, and transcript expression levels were determined by quantitative real-time polymerase chain reactions. KLF4, Kruppel-like factor–4 (gut); SEMA7A, sema domain, immunoglobulin domain, and glycophosphatidyl inositol membrane anchor (semaphorin)–7A; SLC38A4, solute carrier family 38, member 4; TNS1, tensin 1. Values represent means ± SE (n = 8 mice/strain/time), normalized to the sensitive C57BLKS/J control (filtered air, 0 hours). *Significantly different (P < 0.05) from strain-matched control mice, as determined by ANOVA with an all-pairwise multiple comparison procedure (the Holm-Sidak method). †Significantly different (P < 0.05) between the sensitive C57BLKS/J and resistant C57BL/10J murine strain at indicated times, as determined by ANOVA with an all-pairwise multiple comparison procedure (the Holm-Sidak method).