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. 2012 Aug;47(2):234–244. doi: 10.1165/rcmb.2012-0026OC

Figure 7.

Figure 7.

Alanine decreased in sensitive C57BLKS/J murine lungs, but not in resistant C57BL/10J murine lungs, whereas glutamine increased more in the resistant C57BL10/J murine lungs, compared with the sensitive C57BLKS/J murine lungs. Female mice were exposed to filtered air (0 hours, control) or chlorine (45 ppm, 6 or 12 hours), and metabolome profiling was performed with lung tissue. Values are normalized to the sensitive C57BLKS/J control (filtered air, 0 hours) levels, and plots indicate the medians (lines within boxes) with 25% and 75% confidence intervals (borders of the boxes) and 95% confidence intervals (error bars). *Significantly different (P < 0.05) from strain-matched control mice, as determined by ANOVA with an all-pairwise multiple comparison procedure (the Holm-Sidak method). †Significantly different (P < 0.05) between the sensitive C57BLKS/J and resistant C57BL/10J murine strain at indicated times, as determined by ANOVA with an all-pairwise multiple comparison procedure (the Holm-Sidak method).