Table 1. Performance of experimental data for the tRNA model sets.
The first three columns are the experimental data sets: OH (hydroxyl radical footprinting); MPE (methidiumpropyl-EDTA); and, SAXS (small-angle X-ray scattering). The dots indicate the experimental data considered in the model selection procedure. <RMSD> is the average RMSD in Å for 100 selection procedures. <GDT-TS> is the average GDT-TS for 100 selection procedures. N indicates the total number of structures selected. Q is the percentage of structures in the set that have lower RMSD than <RMSD>. Values in parenthesis are the standard deviations. Details of the model selection procedure and GDT-TS computation are given in Materials and Methods
| Experiment | Resolution | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| OH | MPE | SAXS | <RMSD> | <GDT-TS> | N | Q |
| tRNA low [6.1, 25.1] Å | ||||||
| • | 15.92 (0.64) |
0.07 (0.01) |
2406 | 51.5 | ||
| • | 10.97 (0.57) |
0.10 (0.02) |
3277 | 11.6 | ||
| • | 9.11 (1.10) |
0.20 (0.05) |
2974 | 3.2 | ||
| • | • | 10.09 (0.98) |
0.14 (0.03) |
3997 | 7.0 | |
| • | • | 9.16 (1.06) |
0.18 (0.03) |
4241 | 3.3 | |
| • | • | 11.32 (0.65) |
0.10 (0.01) |
3276 | 14.3 | |
| • | • | • | 9.46 (1.06) |
0.17 (0.04) |
4798 | 4.4 |
| tRNA high [3.6, 12.4] Å | ||||||
| • | 5.46 (0.81) |
0.38 (0.81) |
2535 | 36.9 | ||
| • | 5.71 (0.20) |
0.35 (0.20) |
2566 | 47.0 | ||
| • | 6.56 (0.19) |
0.30 (0.02) |
1649 | 74.4 | ||
| • | • | 5.55 (0.20) |
0.38 (0.02) |
2043 | 40.6 | |
| • | • | 6.26 (0.49) |
0.33 (0.03) |
2890 | 65.8 | |
| • | • | 7.51 (0.52) |
0.25 (0.02) |
1995 | 90.8 | |
| • | • | • | 6.34 (0.56) |
0.31 (0.03) |
2760 | 68.8 |