Table 1.
Patient Characteristics at Baseline
| NABTT 0306 | RT+TMZ+EMD All doses combined | RT+TMZ +EMD 500mg | RT+TMZ +EMD 2000mg | NABTT Historical RT+Chemo |
|---|---|---|---|---|
| Characteristics | N=112 | N=46 | N=48 | N=235 |
| Age – year | ||||
| Median | 55.5 | 56.3 | 54.9 | 55 |
| Range | 22--88 | 35—88 | 22--81 | 21--82 |
| Sex – no .(%) | ||||
| Male | 66 (59) | 28 (61) | 29 (60) | 151 (64) |
| Female | 46 (41) | 18 (39) | 19 (40) | 84 (36) |
| Karnofsky Performance Status no. (%) | ||||
| 100 | 27 (24) | 8 (17) | 15 (31) | 33 (18) |
| 90 | 51 (46) | 27 (59) | 18 (38) | 93 (50) |
| 80 | 15 (13) | 3 (7) | 7 (15) | 31 (17) |
| 70 | 15 (13) | 6 (13) | 6 (13) | 21 (11) |
| 60 | 4 (4) | 2 (4) | 2 (4) | 7 (4) |
| Surgical Procedure no. (%) | ||||
| Biopsy | 25 (22) | 10 (22) | 9 (19) | 29 (16) |
| Craniotomy | 86 (77) | 35 (76) | 39 (81) | 156 (84) |
| Other | 1 (1) | 1 (2) | ||
| Corticosteroid Therapy - no. (%) | ||||
| Yes | 82 (74) | 33 (72) | 36 (77) | 157 (67) |
| No | 28 (24) | 13 (28) | 11 (23) | 24 (10) |
| Data missing | 2 (2) | 54 (23) | ||
| Histological Diagnosis - no. (%) | * | |||
| Glioblastoma | 112 (100) | 46 (100) | 48 (100) | 181 (98) |
| Other | 3 (2) | |||
| MGMT no. (%) | ||||
| Methylated | 21 (19) | 11 (24) | 7 (15) | |
| Unmethylated | 48 (43) | 21 (46) | 18 (37) | |
| Unknown | 43 (38) | 14 (30) | 23 (48) |