Table 3.
Comparison of baseline and overall survival for all subjects, those age 18-70 only, in RT+TMZ+EMD to EORTC phase III cohort
Trial | RT+TMZ+EMD | EORTC Phase III |
---|---|---|
Age 18-70 (n=101) | Age 18-70 (n=287) | |
No. of patients (%) | No. of patients (%) | |
Baseline: | ||
Age Median (range), yr | 55 (23-70) | 56 (19-70) |
KPS, 90-100 | 72 (71) | 249 (86) |
Surgery, Debulking | 77 (76) | 239 (83) |
Corticosteroids, yes | 75 (76) | 193 (67) |
Histology, GBM | 101 (100) | 221 (92) |
Outcome: | ||
Median overall survival (95% CI) | 20.7 (17-24) | 14.6 (13-17) |
% overall survival at 24 months (95% CI)* | 41 (31 -51) | 27 (21-32) |
p< 0.05