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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Bone Miner Res. 2012 Sep;27(9):1927–1935. doi: 10.1002/jbmr.1657

Figure 3.

Figure 3

(A) The percent reduction in yield strength associated with adding resorption cavities to cancellous bone, compared to the case without cavities, depended on bone volume fraction (p<0.0001, n=40) and (B) SMI (p<0.0001) when cavities were targeted to regions of highly-strained tissue (filled symbols) but not when they were distributed randomly (unfilled symbols, p>0.43). (C) When resorption cavities were distributed randomly, the percent reduction in yield strength associated with adding such cavities depended on mean trabecular thickness (Tb.Th, p<0.0001).