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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: J Invest Dermatol. 2012 May 24;132(9):2158–2165. doi: 10.1038/jid.2012.144

Figure 2. Effect of [Mg2+]o on the I-V relationship of TRPV3-mediated single-channel current.

Figure 2

(a) Representative single-channel current traces activated by 10 μM 2APB at holding potentials of +60 and -60 mV in the absence and presence of 3 mM Mg2+ in the extracellular solution in CHO cells expressing mTRPV3. (b) I-V relationships of the TRPV3 single-channel current activated by 2APB in CHO cells expressing mTRPV3. Current amplitudes at different holding potentials are normalized to that at -60 mV in the presence of 3 mM Mg2+ in the extracellular solution (marked as asterisk).