CAR rescues ASIC3 current from PSD-95-mediated inhibition. A) Representative acid-evoked currents from COS-7 cells transfected with ASIC3 alone, ASIC3 and PSD-95, or ASIC3, PSD-95 and CAR. B) Mean current densities from cells transfected with the constructs indicated below the graph (n’s are indicated within each bar; *p < 0.01 vs. ASIC3 expressed alone; **p < 0.01 vs. ASIC3 and PSD-95 coexpressed; @p < 0.01 vs. coexpressed ASIC3, PSD-95, and CAR). C) Schematic representation of interactions between ASIC3, PSD-95, and CAR.