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. Author manuscript; available in PMC: 2013 Jul 31.

Published in final edited form as: Cell Oncol (Dordr). 2012 Jan 31;35(2):95–110. doi: 10.1007/s13402-011-0068-y

Fig. 10 — Both uPAR and NHE1 are critical for tumor formation and metastasis in nude mice. A Athymic, nude mice were injected subcutaneously with 5 × 10⁶ of the indicated cells. Control mice (H460 injected) received vehicle, 1% DMSO intraperitonealy whereas animal group indicated with H460 (EIPA) were injected with 10 μg/kg every three days. Animals injected with uPAR or NHE1 knockdown cells did not receive injections. Six weeks post-injection, animals were euthanized and tumor volume determined. Data represent groups of 10 animals. Numbers above bars represent the number of animals out of ten which displayed tumors. A one way Anova with Bonferroni’s Multiple Comparison test with a p<0.001 was used to analyze the data. B. Six week, male athymic nude mice were injected with 5 × 10⁶ cells retro orbitaly and monitored for 40 days post injection.

Fig. 10 — Both uPAR and NHE1 are critical for tumor formation and metastasis in nude mice. A Athymic, nude mice were injected subcutaneously with 5 × 10⁶ of the indicated cells. Control mice (H460 injected) received vehicle, 1% DMSO intraperitonealy whereas animal group indicated with H460 (EIPA) were injected with 10 μg/kg every three days. Animals injected with uPAR or NHE1 knockdown cells did not receive injections. Six weeks post-injection, animals were euthanized and tumor volume determined. Data represent groups of 10 animals. Numbers above bars represent the number of animals out of ten which displayed tumors. A one way Anova with Bonferroni’s Multiple Comparison test with a p<0.001 was used to analyze the data. B. Six week, male athymic nude mice were injected with 5 × 10⁶ cells retro orbitaly and monitored for 40 days post injection.