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. Author manuscript; available in PMC: 2013 Aug 17.
Published in final edited form as: ACS Chem Biol. 2012 Jun 12;7(8):1454–1461. doi: 10.1021/cb300174c

Figure 5.

Figure 5

Circular dichroism spectroscopy data of xRNA-containing siRNAs in siR-U series. Duplexes include the fully natural siR-U-00 (black); single-xRNA-containing duplexes siR-U-01 (green), siR-U-10 (yellow) and siR-U-19 (magenta); and triple-xRNA-containing siR-U-xA3 (blue) and siR-U-xU3 (red). siRNA (5 μM) annealed in 15 mM HEPES–KOH (pH 7.4), 50 mM KOAc and 1 mM MgCl2.