Table 2.
Metabolic Complications, Viral Load, and Immunologic Status by Level of Vitamin D Deficiency
| Variable | All N=463 | Vitamin D sufficient N=77 | Vitamin D insufficient N=111 | Vitamin D deficient N=275 |
|---|---|---|---|---|
| Parathyroid hormone level, pg/ml** | ||||
| Median (IQR) | 46 (31–65) | 40 (26–57) | 45 (29–61) | 49 (34–73) |
| Hyperparathyroidism,‡ no. (%) | ||||
| PTH >65 pg/ml | 104 (26) | 8 (12) | 23 (23) | 73 (30) |
| PTH ≤65 pg/ml | 301 (74) | 57 (88) | 76 (77) | 168 (70) |
| Elevated alkaline phosphatase, hypocalcemia, no. (%) | ||||
| Alk phos >100 U/liter | 165 (36) | 27 (35) | 32 (29) | 106 (39) |
| Adjusted calcium | 188 (41) | 30 (39) | 43 (39) | 115 (42) |
| <9.0 mg/dl | ||||
| Prediabetes or diabetes, no. (%)‡ | ||||
| HbA1c ≥5.7%‡ | 162 (35) | 18 (25) | 38 (37) | 106 (41) |
| Current viral load, no. (%)‡ | ||||
| <50 copies/ml | 300 (65) | 59 (77) | 84 (76) | 157 (57) |
| 50–200 copies/ml | 33 (7) | 4 (5) | 9 (8) | 20 (7) |
| >200 copies/ml | 130 (28) | 14 (18) | 18 (16) | 98 (36) |
| Current CD4 T cell count, no. (%)‡ | ||||
| >350 cells/mm3 | 296 (64) | 52 (68) | 78 (70) | 166 (60) |
| 200–350 cells/mm3 | 94 (20) | 16 (21) | 23 (21) | 55 (20) |
| <200 cells/mm3 | 73 (16) | 9 (12) | 10 (9.0) | 54 (20) |
**p<0.05 by t-test, linear regression, or ANOVA as appropriate for 25(OH)-vitamin D level.
‡
p<0.05 by Chi-square test comparing proportion with and without vitamin D deficiency.
IQR, interquartile range; PTH, parathyroid hormone; Alk phos, alkaline phosphatase.