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. 2012 Sep;28(9):825–832. doi: 10.1089/aid.2011.0325

Table 3.

Characteristics Associated with Vitamin D Deficiency

Variable Odds ratio for vitamin D deficiency (95% CI) p-valuea Adjusted odds ratio for vitamin D deficiencyb(95% CI) p-valuec
Age, years
 18–34 Ref Ref Ref Ref
 35–44 0.33 (0.18, 0.63) <0.01 0.41 (0.20, 0.83) 0.01
 45–54 0.29 (0.16, 0.54) <0.01 0.35 (0.18, 0.71) <0.01
 ≥55 0.32 (0.16, 0.61) <0.01 0.50 (0.24, 1.06) 0.07
Black race
 No Ref Ref Ref Ref
 Yes 2.18 (1.49, 3.19) <0.01 2.26 (1.45, 3.54) <0.01
Weight
 1st quartile Ref Ref Ref Ref
 2nd quartile 0.82 (0.49, 1.37) 0.44 0.80 (0.44, 1.46) 0.47
 3rd quartile 1.23 (0.73, 2.08) 0.45 1.22 (0.66, 2.27) 0.52
 4th quartile 1.19 (0.70, 2.00) 0.52 1.07 (0.58, 1.97) 0.84
Current medications
 MVI 0.27 (0.18, 0.40) <0.01 0.27 (0.17, 0.42) <0.01
 Vitamin D 0.08 (0.02, 0.37) <0.01 0.13 (0.03, 0.64) 0.01
Current CD4 T cell count, cells/mm3
 >350 Ref Ref Ref Ref
 200–350 1.10 (0.69, 1.77) 0.68 0.77 (0.45, 1.33) 0.35
 <200 2.23 (1.26, 3.94) 0.01 1.50 (0.76, 2.93) 0.24
Current viral load, copies/mL
 <50 Ref Ref Ref Ref
 50–200 1.40 (0.67, 2.92) 0.37 1.13 (0.49, 2.60) 0.77
 >200 2.79 (1.76, 4.41) <0.01 2.97 (1.48, 5.97) <0.01
Current antiretroviral therapy, no. (%)
 None Ref Ref Ref Ref
 EFV-based 0.79 (0.44, 1.42) 0.43 3.06 (1.32, 7.13) 0.01
 PI-based 0.51 (0.30, 0.88) 0.02 1.50 (0.69, 3.29) 0.31
 Other 0.44 (0.20, 0.96) 0.04 1.82 (0.65, 5.07) 0.25
a

Univariate analysis of association with vitamin D deficiency.

b

Variables associated with vitamin D deficiency with p≤0.10 were included in multivariate logistic regression (i.e., age, black race/ethnicity, current use of MVI, current use of vitamin D supplements, current CD4 count, current viral load, current antiretroviral therapy).

c

Multivariate analysis of association with vitamin D deficiency.