Table 3.
Variable | Odds ratio for vitamin D deficiency (95% CI) | p-valuea | Adjusted odds ratio for vitamin D deficiencyb(95% CI) | p-valuec |
---|---|---|---|---|
Age, years | ||||
18–34 | Ref | Ref | Ref | Ref |
35–44 | 0.33 (0.18, 0.63) | <0.01 | 0.41 (0.20, 0.83) | 0.01 |
45–54 | 0.29 (0.16, 0.54) | <0.01 | 0.35 (0.18, 0.71) | <0.01 |
≥55 | 0.32 (0.16, 0.61) | <0.01 | 0.50 (0.24, 1.06) | 0.07 |
Black race | ||||
No | Ref | Ref | Ref | Ref |
Yes | 2.18 (1.49, 3.19) | <0.01 | 2.26 (1.45, 3.54) | <0.01 |
Weight | ||||
1st quartile | Ref | Ref | Ref | Ref |
2nd quartile | 0.82 (0.49, 1.37) | 0.44 | 0.80 (0.44, 1.46) | 0.47 |
3rd quartile | 1.23 (0.73, 2.08) | 0.45 | 1.22 (0.66, 2.27) | 0.52 |
4th quartile | 1.19 (0.70, 2.00) | 0.52 | 1.07 (0.58, 1.97) | 0.84 |
Current medications | ||||
MVI | 0.27 (0.18, 0.40) | <0.01 | 0.27 (0.17, 0.42) | <0.01 |
Vitamin D | 0.08 (0.02, 0.37) | <0.01 | 0.13 (0.03, 0.64) | 0.01 |
Current CD4 T cell count, cells/mm3 | ||||
>350 | Ref | Ref | Ref | Ref |
200–350 | 1.10 (0.69, 1.77) | 0.68 | 0.77 (0.45, 1.33) | 0.35 |
<200 | 2.23 (1.26, 3.94) | 0.01 | 1.50 (0.76, 2.93) | 0.24 |
Current viral load, copies/mL | ||||
<50 | Ref | Ref | Ref | Ref |
50–200 | 1.40 (0.67, 2.92) | 0.37 | 1.13 (0.49, 2.60) | 0.77 |
>200 | 2.79 (1.76, 4.41) | <0.01 | 2.97 (1.48, 5.97) | <0.01 |
Current antiretroviral therapy, no. (%) | ||||
None | Ref | Ref | Ref | Ref |
EFV-based | 0.79 (0.44, 1.42) | 0.43 | 3.06 (1.32, 7.13) | 0.01 |
PI-based | 0.51 (0.30, 0.88) | 0.02 | 1.50 (0.69, 3.29) | 0.31 |
Other | 0.44 (0.20, 0.96) | 0.04 | 1.82 (0.65, 5.07) | 0.25 |
Univariate analysis of association with vitamin D deficiency.
Variables associated with vitamin D deficiency with p≤0.10 were included in multivariate logistic regression (i.e., age, black race/ethnicity, current use of MVI, current use of vitamin D supplements, current CD4 count, current viral load, current antiretroviral therapy).
Multivariate analysis of association with vitamin D deficiency.