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. 2012 May 11;120(7):1510–1515. doi: 10.1182/blood-2012-01-405514

Table 3.

Absolute and relative risks for VTE in relatives dependent on IT

Type of IT Exposure time, y Event, n Annual incidence, % (95% CI) Hazard ratio,* % (95% CI) P
AT/PC/PS 463 13 2.82 (1.63-4.80) 25.7 (12.2-54.2) < .001
FV G1691A 2783 7 0.25 (0.12-0.53) 1.7 (0.7-4.4) .24
FII G20210A 1192 5 0.42 (0.17-1.01) 2.6 (0.9-7.6) .09
Combined defects 258 6 2.33 (1.04-5.19) 19.6 (7.7-49.6) < .01
No IT 13 567 14 0.10 (0.06-0.17) 1 1
Total 18 278 47 0.26 (0.19-0.34)

IT indicates inherited thrombophilia; and VTE, venous thromboembolism.

*

Adjusted for age and sex.