Treatment Intensification Score (per 0.1 unit)
|
1.64 (1.58, 1.71) |
<0.01 |
Adherent vs. Non-adherent (≥80% PDC)
|
1.18 (0.94, 1.47) |
0.15 |
Number of blood pressures over follow-up
|
0.99 (0.97, 1.01) |
0.37 |
Medication classes at time of outcome BP status
|
|
|
ACE/ARB |
0.74 (0.59, 0.94) |
0.01 |
Diuretic Thiazide, Loop, CAI or K-sparing |
1.64 (1.27, 2.12) |
<0.01 |
K-sparing diuretic only |
0.81 (0.62, 1.08) |
0.15 |
Beta blocker |
0.88 (0.71, 1.10) |
0.27 |
Calcium channel blocker |
0.79 (0.64, 0.97) |
0.03 |
Alpha 1 and 2 Adrenergic blocker |
0.70 (0.52, 0.94) |
0.02 |
Other (Peripheral Vasodilator and Reserpine) |
0.75 (0.44, 1.27) |
0.28 |
Demographics
|
|
|
Gender - Male vs. Female |
0.95 (0.77, 1.16) |
0.59 |
Race |
|
0.46 |
Black vs. White |
1.16 (0.81, 1.66) |
0.41 |
Missing vs. White |
0.92 (0.64, 1.31) |
0.63 |
Other vs. White |
0.87 (0.68, 1.11) |
0.25 |
Smoking status - current vs. not |
0.99 (0.70, 1.38) |
0.94 |
Age at index in years |
1.00 (0.99, 1.01) |
0.74 |
Hypertension registry entry year |
1.10 (1.02, 1.19) |
0.02 |
Baseline Co-morbidities
|
|
|
Albuminuria |
0.85 (0.29, 2.48) |
0.76 |
Alcohol abuse |
1.25 (0.73, 2.12) |
0.42 |
Angina |
2.01 (0.70, 5.79) |
0.19 |
Asthma |
1.03 (0.74, 1.42) |
0.87 |
Atrial Fibrillation |
1.17 (0.66, 2.05) |
0.59 |
Bipolar |
1.33 (0.38, 4.68) |
0.66 |
Chronic Kidney Disease |
0.78 (0.51, 1.20) |
0.25 |
Diabetes Mellitus |
0.96 (0.75, 1.22) |
0.71 |
Depression |
1.08 (0.77, 1.51) |
0.65 |
Migraine |
1.29 (0.66, 2.53) |
0.46 |
Other Arrhythmias |
0.93 (0.45, 1.91) |
0.85 |
Peripheral Vascular Disease |
1.34 (0.69, 2.60) |
0.39 |
Schizophrenia |
1.03 (0.18, 5.84) |
0.98 |
Sleep Apnea |
1.56 (0.74, 3.26) |
0.24 |