Table 4.
Comparing factors affecting physical and mental health in Avonex and CinnoVex groups.
| Time-varying covariate | Avonex | CinnoVex | P | |||||
|---|---|---|---|---|---|---|---|---|
| Baseline | Change∗ | P | Baseline | Change | P | Baseline | Change | |
| EDSS | 1.9 | 0.1 | 0.489 | 1.5 | 0.2 | 0.401 | 0.104 | 0.231 |
| MSQOL-54 measures | ||||||||
| Physical health composite score | 61.8 | 1.2 | 0.677 | 59.8 | 0.0 | 0.884 | 0.608 | 0.377 |
| Mental health composite score | 57.4 | −2.2 | 0.197 | 53.6 | 1.6 | 0.845 | 0.392 | 0.841 |
| Physical function | 12.8 | 0.2 | 0.587 | 12.2 | 0.2 | 0.475 | 0.465 | 0.324 |
| Health perception | 9.9 | 0.2 | 0.559 | 9.9 | −0.5 | 0.127 | 0.932 | 0.251 |
| Energy | 6.2 | −0.25 | 0.185 | 5.74 | 0.1 | 0.541 | 0.316 | 0.828 |
| Role limitation—physical | 7.6 | −0.2 | 0.914 | 6.3 | −0.0 | 0.958 | 0.223 | 0.201 |
| Bodily pain | 7.6 | 0.1 | 0.640 | 7.5 | −0.17 | 0.185 | 0.850 | 0.356 |
| Sexual function | 1.7 | 0.27 | 0.411 | 2.6 | 0.2 | 0.585 | 0.172 | 0.189 |
| Social function | 8.2 | 0.2 | 0.516 | 8.3 | −0.0 | 0.877 | 0.904 | 0.756 |
| Health distress—physical | 7.4 | −0.1 | 0.757 | 6.9 | 0.0 | 0.685 | 0.434 | 0.587 |
| Health distress—mental | 9.4 | −0.1 | 0.757 | 9.3 | 0.1 | 0.685 | 0.434 | 0.587 |
| Overall quality of life | 6.2 | 2.4 | 0.536 | 5.9 | 0.1 | 0.733 | 0.505 | 0.491 |
| Cognitive function | 11.2 | −0.6 | 0.016 | 10.6 | −0.5 | 0.050 | 0.494 | 0.548 |
| Emotional well-being | 16.1 | −0.2 | 0.713 | 15.3 | 0.6 | 0.205 | 0.516 | 0.995 |
| Role limitation—emotional | 13.8 | −0.8 | 0.844 | 12.0 | −0.1 | 0.896 | 0.442 | 0.544 |
| Satisfaction with sexual function | 19.1 | 5.6 | 0.221 | 30.2 | 1.5 | 0.698 | 0.169 | 0.368 |
| Change in health | 48.5 | 1.9 | 0.669 | 50.5 | 4.2 | 0.275 | 0.760 | 0.418 |
∗ Change after a year.