Table 3.
Mean Density of Pneumococcal Carriage in Infected Individuals During the Prevaccination and Postvaccination Cross-Sectional Surveys in Vaccinated Villages and Control Villages, by Age at Sample Collection
Age ≤ 5 Years |
Age > 5 Years |
||||||||
---|---|---|---|---|---|---|---|---|---|
Study Arm, Serotype Group | Prevaccination | Postvaccinationa | Difference (95% CI) | P | Prevaccination | Postvaccinationa | Difference (95% CI) | P | Pintb |
Vaccinated villages | |||||||||
VT | 2.87 | 2.48 | −0.39 (−0.82 to 0.04) | .071 | 2.14 | 1.78 | −0.36 (−0.64 to −0.07) | .021 | .902 |
NVT | 2.72 | 2.08 | −0.64 (−1.28 to 0.01) | .052 | 2.48 | 1.91 | −0.57 (−0.90 to −0.25) | .003 | .582 |
All | 2.57 | 2.11 | −0.46 (−0.97 to 0.04) | .067 | 2.44 | 1.88 | −0.56 (−0.83 to −0.29) | .001 | .702 |
Control villages | |||||||||
VT | 2.70 | 1.94 | −0.76 (−1.49 to −0.04) | .042 | 2.42 | 1.78 | −0.64 (−1.00 to −0.28) | .003 | .685 |
NVT | 2.90 | 2.03 | −0.87 (−1.46 to −0.28) | .010 | 2.45 | 1.74 | −0.71 (−1.06 to −0.36) | .001 | .895 |
All | 2.76 | 1.99 | −0.78 (−1.19 to −0.36) | .002 | 2.44 | 1.75 | −0.69 (−1.01 to −0.37) | .001 | .696 |
Data are mean densities, expressed in arbitrary units, as defined in the Methods section.
Abbreviations: CI, confidence interval; NVT, non–vaccine-type pneumococci; VT, vaccine-type pneumococci.
a Data are for all 3 postvaccination cross-sectional surveys combined.
b P value for interaction between group (control or vaccinated) and age category.