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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: Structure. 2012 Jul 5;20(8):1414–1424. doi: 10.1016/j.str.2012.05.015

Figure 4. Effect of domain swapping on the oxyanion hole residue, N141.

Figure 4

(A) Superposition of one Ubp8 monomer in the domain-swapped DUBm complex lacking the Sgf11-ZnF (green) with Ubp8 in intact DUBm complex (gray) showing altered position of N141.

(B) Superposition as in (A) showing the second Ubp8 monomer (purple) in the domain-swapped complex in which N141 disordered.

(C, D) Superpositions as in (A) showing Ubp8 in the domain-swapped DUBm-ΔSgf11-ZnF complex containing Ubp8S144N. Coloring as in (A)