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. 2012 Aug 21;10(8):e1001379. doi: 10.1371/journal.pbio.1001379

Figure 1. Overview of the evolutionary method used to discover a novel vascular disrupting agent.

Figure 1

Strict reliance on the evolutionary conservation of the relevant gene module allowed for an experimental design exploiting the unique experimental advantages of each model organism, thus speeding the search for novel angiogenesis inhibitors. (Vector female silhouette under Creative Commons Attribution 2.0 from ‘Keep Fit’ Vector Pack, Blog.SpoonGraphics.)