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Latency to eat solid rat chow after third intracerebroventricular, 2-μl bolus injections of ghrelin or ACSF vehicle in rats (n = 10). The large latency to eat after vehicle injection reflects the low meal frequency at the time of injection (mid-light cycle) in these nocturnal rats. Ghrelin at both doses significantly decreased the latency to eat. *P < 0.001 for each dose of ghrelin compared with vehicle.
