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Number of lever bar presses during a progressive-ratios self-administration of a 5% sucrose solution. The results indicate that ghrelin administration enhanced rats' motivation to eat. Depending on the dose administered, the behavioral effect of ghrelin was equal to or greater than that of 24 h of food deprivation immediately preceding the test. *P < 0.01 relative to the vehicle control condition. †P < 0.01 relative to prior 24-h fasting.
