Fig. 4.

Effect of the cyclooxygenase (COX) inhibitor indomethacin (Indo, 10 μM) on myogenic tone in myometrial arteries from nonpregnant and pregnant women. Indo had no effect on myogenic tone in nonpregnant (A: ●, −Indo vs. ○, +INDO; n = 5, P = 0.66,) and pregnant women (B: ■, −Indo vs. □, +Indo; n = 5, P = 0.25). Data were analyzed by ANOVA doubly repeated measures analysis where pregnancy status is the between-subjects factor and the absence or presence of INDO and pressure are the within-subject repeated factors.