Fig. 5.
Fentanyl-evoked TE prolongation before and after intra-caudomedial nucleus of solitary tract (mNTS) microinjection of DPAT without and with local WAY-100635 pretreatment (WAY+DPAT). A: typical recordings with arrows indicating the onset of bolus injections of fentanyl via the right atrium. B: group data. n = 7; values are means ± SE; **P < 0.01, compared with baseline values (“0”) obtained before injecting fentanyl into the right atrium; †P < 0.05 and ‡P < 0.01, compared with control (CON = without systemic or local treatment) or WAY+DPAT. C: bilateral microinjection locations labeled by fluorescent microbeads. 10N, dorsal motor nucleus of vagus; 12N, hypoglossal nucleus; CC, central canal; Gr, gracile nucleus.