Comparison of baseline cardiorespiratory activities and their responses to systemic DPAT challenge before and after pretreating the mNTS with WAY. CON, before intra-mNTS injection of WAY; DPAT, systemic DPAT challenge; WAY, intra-mNTS injection of WAY; WAY+DPAT, intra-mNTS injection of WAY followed by systemic DPAT challenge. n = 8; values are means ± SE; *P < 0.05 and **P < 0.01, compared with CON; †P < 0.05 and ‡P < 0.01, compared with WAY. Note: all data of WAY+DPAT are not significantly different from those of DPAT alone (P > 0.05). PetCO2, end-tidal pressure of carbon dioxide.