RSNA, MAP, and HR responses to losartan microinjected into the PVN. A: segments of original recordings from individual rats from each experimental group showing responses of RSNA, int.RSNA, MAP, and HR to losartan (100 nmol) microinjected into the PVN. B: mean changes in RSNA, MAP, and HR following microinjections of losartan into the PVN. *P < 0.05 vs. sham with the same dose of losartan; #P < 0.05 vs. Sed with the same dose of losartan.