Fig. 1.

Wild-type (WT) and Kv3.2 knockout (KO) mice under ketamine-xylazine anesthesia have similar amounts of fast (20–50 Hz) and slow (0.1–15 Hz) oscillations in the spontaneous cortical local field potentials (LFP). A: LFPs (Cx1-Cx4) show spontaneous slow oscillation with a mean frequency of 1.3 Hz. Gamma oscillations crowned the negative phase of the LFPs as shown by the filtered (20–50 Hz) traces (details 1 and 2, amplified from the sections indicated by dotted boxes). B: histograms represent total power between 0.1 and 15 Hz and between 20 and 50 Hz calculated from 2-min periods of stable spontaneous LFPs (n = 5 epochs, n = 10 mice; 5 KO and 5 WT).