Table 5.
Differential expressed genes in PPC + S group involved in tissue homeostasis and integrative intestine functions (mean fold change of PPC control group levels)
| Gene | Fold change ± SE |
|---|---|
|
Exocytosis | |
| Exosome complex exonuclease RRP42 |
1.85 ± 0.12 |
| Exosome component Rrp46 |
1.75 ± 0.12 |
| Gelsolin |
9.28 ± 3.07 |
| Signal recognition particle receptor subunit beta |
2.47 ± 0.55 |
|
Adhesion and glycans | |
| Occludin |
1.72 ± 0.21 |
| Phospholipase D2 |
2.03 ± 0.18 |
| Gap junction Cx32.2 protein |
−2.54 ± 0.40 |
| Rho-related GTP-binding protein RhoG precursor |
1.79 ± 0.34 |
| Kalirin, RhoGEF kinase isoform 3 |
1.63 ± 0.02 |
| Myosin phosphatase-Rho interacting protein isoform 1 |
−1.88 ± 0.61 |
| Myosin IB |
15.3 ± 4.29 |
| Tropomyosin alpha-3 chain |
1.71 ± 0.24 |
| Tropomyosin-1 alpha chain |
1.77 ± 0.24 |
| Protocadherin 20 |
−2.21 ± 0.29 |
| Similar to laminin beta 2-like chain |
−2.43 ± 0.51 |
| Epithelial cadherin |
−3.06 ± 0.61 |
| Aspartylglucosaminidase |
−2.23 ± 0.42 |
| Glucosamine 6-phosphate N-acetyltransferase |
1.92 ± 0.33 |
| Beta-1,3-N-acetylglucosaminyltransferase 7 |
4.28 ± 0.68 |
| Alpha-1,3-fucosyltransferase |
2.65 ± 0.83 |
| D-glucosaminylasparagine amidase F |
−1.85 ± 0.08 |
| Alpha-N-acetylgalactosaminidase |
−2.29 ± 0.5 |
| Glypican 1 |
−2.34 ± 0.39 |
| Hyaluronan and proteoglycan link protein 4 |
−2.41 ± 0.16 |
| Di-N-acetylchitobiase |
−2.46 ± 0.56 |
| N-acetylglucosamine-6-sulfatase |
−3.16 ± 0.79 |
| Beta-hexosaminidase beta chain |
−3.45 ± 1.09 |
| N-acetylneuraminate lyase |
−4.3 ± 1.47 |
| Mannosidase, alpha, class 2B, member 1 |
−8.25 ± 3.7 |
|
Growth factors, regulators | |
| Angiogenin-1 |
−2.11 ± 0.16 |
| Bone morphogenetic protein 7 |
−2.11 ± 0.16 |
| Angiopoietin-related protein 4 |
−2.31 ± 0.38 |
| Connective tissue glrowth factor |
−2.26 ± 0.32 |
| Class B basic helix-loop-helix protein 2 |
−1.68 ± 0.19 |
| Class B basic helix-loop-helix protein 3 |
−5.85 ± 2.34 |
| Transmembrane glycoprotein NMB |
−2.27 ± 0.10 |
| TGFbeta-inducible early growth response protein 3 |
−2.38 ± 0.62 |
| Guanylin |
2.37 ± 0.34 |
| Fibroblast growth factor 12 |
−2.53 ± 0.33 |
|
Cellular stress | |
| Ubiquitin |
10.80 ± 2.85 |
| 60 kDa heat shock protein, mitochondrial |
2.27 ± 0.54 |
| Heat shock cognate 70 kDa protein |
3.14 ± 0.31 |
| Heat shock cognate 71 kDa protein |
3.02 ± 0.26 |
| Heat shock protein HSP 90-alpha |
1.80 ± 0.09 |
| Heat shock protein 67B2 | −2.31 ± 0.38 |