Table 1. Cowpea bruchid midgut genes coregulated by bergapten and scN.
| Category | Accession# | Putative Function (Abbreviation) | Fold changea | |
| Bergapten | scN | |||
| Sugar Metabolism | ||||
| FK668918 | alpha-Amylase (AMY1) | 0.43 | 2.14 | |
| FK668899 | alpha-Glucosidase (AGL1) | 0.26 | 2.90 | |
| FK668900 | alpha-Glucosidase (AGL2) | 0.47 | 2.46 | |
| FK668901 | alpha-Glucosidase (AGL3) | 0.37 | 3.05 | |
| FK668902 | alpha-Glucosidase (AGL4) | 0.18 | 2.11 | |
| FK668936 | beta-1,4-Mannanase 1 (MAN2) | 0.13 | 3.69 | |
| FK668881 | beta-Galactosidase (BGL2) | 0.46 | 9.28 | |
| FK668883 | beta-Galactosidase (BGL4) | 0.40 | 5.41 | |
| FK668907 | beta-Glucosidase (BGA4) | 0.40 | 2.18 | |
| FK668908 | beta-Glucosidase (BGA5) | 0.27 | 2.48 | |
| FK668909 | beta-Glucosidase (BGA6) | 0.11 | 2.07 | |
| FK668910 | beta-Glucosidase (BGA7) | 0.49 | 4.52 | |
| FK668911 | beta-Glucosidase (BGA8) | 0.43 | 6.19 | |
| FK668914 | beta-Glucosidase (BGA11) | 0.41 | 3.61 | |
| FK668915 | beta-Glucosidase (BGA12) | 0.25 | 2.37 | |
| FK669587 | Glycoside hydrolase family protein 5 (GH5) | 0.16 | 3.81 | |
| GW917132 | Glycoside hydrolase family protein 28 (GH28-1) | 0.23 | 2.28 | |
| FK668916 | Glycosyl hydrolase family 31 protein (GH31-1) | 0.38 | 2.51 | |
| FK668917 | Glycosyl hydrolase family 31 protein (GH31-2) | 0.32 | 2.64 | |
| GW917355 | Mitochondrial enolase superfamily member 1 (ENOSF1b) | 0.29 | 6.95 | |
| FK668996 | Pectate lyase (PEL2) | 0.45 | 2.02 | |
| FK668897 | beta-Mannosidase A (MANBA) | 8.65 | 0.01 | |
| Protein metabolism | ||||
| FK668971 | Carboxypeptidase, vitellogenic-like (CPVL1) | 0.37 | 3.79 | |
| FK668961 | Cathepsin B (CatB6) | 0.19 | 3.40 | |
| FK668962 | Cathepsin B (CatB7) | 0.31 | 2.20 | |
| FK668948 | Cathepsin L (CatL1) | 0.36 | 2.39 | |
| FK668951 | Cathepsin L (CatL4) | 0.27 | 4.90 | |
| FK668952 | Cathepsin L (CatL5) | 0.29 | 4.03 | |
| FK668953 | Cathepsin L (CatL6) | 0.32 | 3.77 | |
| FK669001 | Cystathionine beta-lyase (CBL2) | 6.00 | 0.45 | |
| FK669322 | Eukaryotic translation initiation factor 4 gamma 2 (eIF4G2-1) | 2.53 | 0.44 | |
| FK669004 | Glutaminyl-peptide cyclotransferase (QPCT) | 0.47 | 2.84 | |
| FK669330 | HBS1/Elongation factor 1 alpha-like protein (HBS1) | 6.94 | 0.09 | |
| FK669008 | Homocysteine S-methyltransferase (HMT) | 2.28 | 0.46 | |
| FK669005 | Phosphoserine aminotransferase (PSAT1-1) | 3.35 | 0.24 | |
| FK669006 | Phosphoserine aminotransferase (PSAT1-2) | 2.00 | 0.34 | |
| FK669007 | Phosphoserine aminotransferase (PSAT1-3) | 3.13 | 0.25 | |
| FK668974 | Plasma glutamate carboxypeptidase (PGCP1) | 0.39 | 2.70 | |
| FK668976 | Plasma glutamate carboxypeptidase (PGCP3) | 0.49 | 3.22 | |
| FK669010 | Prolyl-4-hydroxylase-alpha EFB (PH4alphaEFB1) | 4.31 | 0.02 | |
| FK669011 | Prolyl-4-hydroxylase-alpha EFB (PH4alphaEFB2) | 4.71 | 0.02 | |
| FK668967 | Retinoid-inducible serine carboxypeptidase (RISC2) | 0.46 | 2.04 | |
| FK668979 | Trypsinogen RDOT3 (RDOT3) | 0.35 | 3.34 | |
| Lipid metabolism | ||||
| FK669017 | 24-Dehydrocholesterol reductase (DHCR24-1) | 0.45 | 2.31 | |
| FK669019 | 24-Dehydrocholesterol reductase (DHCR24-3) | 0.49 | 2.29 | |
| FK669021 | Aldo-keto reductase (AKR1) | 0.35 | 2.48 | |
| FK669046 | Glucosylceramidase (GBA) | 0.47 | 4.14 | |
| Other metabolism | ||||
| FK669060 | 5-Oxoprolinase (ATP-hydrolysing) (OPLAH) | 0.44 | 2.20 | |
| FK669054 | Glyoxylate reductase hydroxypyruvate reductase (GRHPR) | 0.44 | 3.52 | |
| Transport | ||||
| FK669075 | Solute carrier family facilitated glucose transporter member 8 (GLUT1) | 0.45 | 2.63 | |
| FK669446 | Solute carrier family facilitated glucose transporter member 8 (GLUT3) | 2.31 | 0.18 | |
| FK669068 | Sugar transporter (SUT1) | 2.17 | 2.27 | |
| FK669069 | Sugar transporter (SUT2) | 0.45 | 2.26 | |
| FK669103 | Vacuolar H ATPase 100-2 (VHA100-2) | 3.27 | 0.04 | |
| Signaling/Transcriptional regulation | ||||
| FK669149 | Klotho (Klotho) | 0.12 | 2.62 | |
| Detoxification | ||||
| FK669179 | Catalase (CAT1) | 2.85 | 0.24 | |
| FK669180 | Catalase (CAT2) | 3.01 | 0.31 | |
| FK669165 | Cytochrome P450 (CYP6G1-2) | 4.65 | 0.39 | |
| FK669166 | Cytochrome p450 (CYP6G1-3) | 8.06 | 0.37 | |
| FK669192 | Esterase-6 precursor (EST2) | 0.43 | 2.23 | |
| FK669177 | Glutathione S-transferase (GST) | 3.48 | 0.48 | |
| FK669176 | Peroxidase precursor (POD) | 0.20 | 0.32 | |
| Ubiquitination | ||||
| FK669204 | Ubiquitin-conjugating enzyme E2-17 kDa (E2(17)KB) | 2.50 | 0.35 | |
| Defense | ||||
| FK669230 | Drosomycin-like I (DrsL1-1) | 18.97 | 0.03 | |
| FK669231 | Drosomycin-like I (DrsL1-2) | 21.75 | 0.02 | |
| Development | ||||
| FK669269 | Extramacrochaetae protein (EMC) | 2.11 | 0.41 | |
| FK669260 | Juvenile hormone esterase (JHE7) | 0.36 | 2.04 | |
| FK669270 | Laccase 2 (LAC2) | 3.40 | 0.09 | |
| Neuronal function | ||||
| FK669050 | AMP-dependent CoA ligase (CL) | 2.33 | 0.15 | |
| FK669281 | Synaptic vesicle membrane protein VAT-1 homolog (VAT1-1) | 2.03 | 0.21 | |
| FK669282 | Synaptic vesicle membrane protein VAT-1 homolog (VAT1-2) | 2.18 | 0.12 | |
| Cellular function | ||||
| FK669309 | Actin binding protein (ABP2) | 3.59 | 0.15 | |
| FK669368 | CD9 antigen (CD9-2) | 3.41 | 0.32 | |
| FK669316 | Failed axon connections (FAX) | 2.72 | 0.14 | |
| FK669354 | Guanosine monophosphate reductase (GMPR) | 2.13 | 0.17 | |
| FK669332 | LIM domain protein (LIM2) | 2.32 | 0.17 | |
| FK669357 | Lysosomal acid phosphatase 2 (LAP1) | 0.46 | 9.50 | |
| FK669306 | Tubulin-specific chaperone a (TBCA) | 2.08 | 0.42 | |
| FK669348 | 40 kDa salivary protein SP11 (SP11) | 0.16 | 5.92 | |
| Other functions | ||||
| FK669624 | BCL2 adenovirus e1b 19 kda protein-interacting (BNIP3L) | 2.03 | 0.36 | |
a
: Numbers shaded gray indicate genes down-regulated by two-fold or more (P≤0.05) in response to dietary bergapten or scN, Unshaded are up-regulated, and underlined indicate the genes are induced or repressed by both bergapten or scN.