Table 2.
The factors associated with 1-year mortality
| |
Non-survivors |
Survivors |
Pvalue |
|---|---|---|---|
| (n = 42) | (n = 261) | ||
| Sex (male/female) |
18/24 |
113/148 |
0.958 |
| Age (years) |
45.4 ± 13.4 |
43.6 ± 12.2 |
0.389 |
| WFNS score on admission |
4.0 ± 0.7 |
2.1 ± 1.0 |
<0.001 |
| Modified Fisher score on admission |
4.2 ± 0.6 |
2.5 ± 0.8 |
<0.001 |
| Aneurysmal location |
|
|
0.614 |
| Posterior communication artery |
8 (19.0%) |
75 (28.7%) |
|
| Internal carotid artery |
6 (14.3%) |
37 (14.2%) |
|
| Anterior communication artery |
9 (21.4%) |
57 (21.8%) |
|
| Middle cerebral artery |
7 (16.7%) |
38 (14.6%) |
|
| Anterior cerebral artery |
6 (14.3%) |
29 (11.1%) |
|
| Posterior cerebral artery |
4 (9.5%) |
19 (7.3%) |
|
| Vertebral artery |
2 (4.8%) |
6 (2.3%) |
|
| Surgery |
21 (50.0%) |
165 (63.2%) |
0.102 |
| Aneurysmal size (mm) |
11.1 ± 5.3 |
6.6 ± 4.5 |
<0.001 |
| Rebleeding |
10 (23.8%) |
6 (2.3%) |
<0.001 |
| Acute hydrocephalus |
25 (59.5%) |
65 (24.9%) |
0.001 |
| Intracerebral hemorrhage |
19 (45.2%) |
20 (7.7%) |
<0.001 |
| Intraventricular hemorrhage |
37 (88.1%) |
35 (13.4%) |
<0.001 |
| External ventricular drain |
38 (90.5%) |
71 (27.2%) |
<0.001 |
| Angiographic vasospasm |
38 (90.5%) |
93 (35.6%) |
<0.001 |
| Computed tomography ischemia |
18 (42.9%) |
32 (12.3%) |
<0.001 |
| Admission time (hours) |
5.5 ± 4.4 |
4.6 ± 3.5 |
0.128 |
| Seizure |
9 (21.4%) |
35 (13.4%) |
0.171 |
| Plasma C-reactive protein level (mg/L) |
8.7 ± 3.3 |
6.9 ± 2.6 |
<0.001 |
| plasma D-dimer level (mg/L) |
2.4 ± 1.0 |
2.0 ± 1.0 |
0.015 |
| Plasma HMGB1 level (ng/mL) | 12.7 ± 3.2 | 7.9 ± 3.2 | <0.001 |
Numerical variables are presented as mean ± standard deviation. Categorical variables are expressed as counts (percentage). Numerical variables were analyzed by Mann–Whitney U-test or unpaired Student t test. Categorical variables were analyzed by chi-square test or Fisher exact test. HMGB1, high mobility group box-1; n, number of patients; WFNS, World Federation of Neurological Surgeons.