Table 9.
Receiver operating characteristic curve analysis of factors predicting 1-year poor functional outcome among 303 patients
| HMGB1 | WFNS score | Modified Fisher score | |
|---|---|---|---|
| Criterion |
>8.9 ng/mL |
>2 |
>2 |
| Area under curve |
0.858 |
0.909 |
0.902 |
| 95% confidence interval |
0.813 to 0.895 |
0.871 to 0.939 |
0.863 to 0.933 |
| Sensitivity |
84.4 |
96.7 |
95.6 |
| 95% confidence interval |
75.3 to 91.2 |
90.6 to 99.3 |
89.0 to 98.7 |
| Specificity |
77.0 |
74.7 |
69.5 |
| 95% confidence interval |
70.8 to 82.5 |
68.3 to 80.3 |
62.8 to 75.6 |
| + likelihood ratio |
3.67 |
3.81 |
3.13 |
| 95% confidence interval |
3.3 to 4.1 |
3.5 to 4.2 |
2.8 to 3.5 |
| - likelihood ratio |
0.2 |
0.045 |
0.064 |
| 95% confidence interval |
0.1 to 0.3 |
0.01 to 0.1 |
0.02 to 0.2 |
| P value | Reference | 0.104 | 0.163 |
HMGB1, high mobility group box-1; WFNS, World Federation of Neurological Surgeons.