Table 1.
Frequencies and incidence rates for all primary malignant brain and CNS germ cell tumors estimated by the Japan Cancer Surveillance Research Group (2004–2006; 14 registries) and Surveillance, Epidemiology, and End Results (2004–2008; 17 registries) data. Age-adjusted to the 2000 US Population
| Characteristics | JCSRG (malignant) |
SEER (malignant) |
||
|---|---|---|---|---|
| n (%) | Incidence (95% CI) | n (%) | Incidence (95% CI) | |
| All malignant GCTs | 122 (100.0) | 0.096 (0.079–0.114) | 289 (100.0) | 0.075 (0.067–0.084) |
| Male | 93 (76.2) | 0.143 (0.113–0.172) | 233 (80.6) | 0.118 (0.103–0.134) |
| Female | 29 (23.8) | 0.046 (0.029–0.064) | 56 (19.4) | 0.030 (0.023–0.039) |
| 00–14 ya | 43 (35.3) | 0.188 (0.132–0.244) | 119 (41.2) | 0.147 (0.122–0.176) |
| 15–29 ya | 65 (53.3) | 0.224 (0.169–0.278) | 141 (48.8) | 0.175 (0.147–0.207) |
| 30+ ya | 14 (11.5) | 0.013 (0.006–0.019) | 29 (10.0) | 0.014 (0.009–0.020) |
| Primary site | ||||
| Pineal (C75.3) | 49 (40.2) | 0.039 (0.028–0.049) | 134 (46.4) | 0.035 (0.029–0.041) |
| Nonpineal (C700–729, 751–752) | 73 (59.8) | 0.058 (0.044–0.071) | 155 (53.6) | 0.040 (0.034–0.047) |
| Suprasellar Regionb | 51 | 0.038 (0.027–0.049) | 88 | 0.023 (0.018–0.028) |
| Ventricle | – | – | 28 | 0.007 (0.005–0.010) |
| Brain, NOS | 36 | 0.027 (0.018–0.036) | 40 | 0.010 (0.007–0.014) |
| Pituitary gland | 13 | 0.010 (0.004–0.015) | 19 | 0.005 (0.003–0.008) |
| Cerebrum | 16 | 0.014 (0.007–0.021) | 29 | 0.007 (0.005–0.011) |
| All other sites | – | – | 38 | 0.010 (0.007–0.014) |
| Selected histologies | ||||
| Germinoma | 100 (82.0) | 0.078 (0.062–0.093) | 224 (77.5) | 0.058 (0.051–0.066) |
| Teratoma | 7 (5.7) | 0.006 (0.002–0.011) | 21 (7.3) | 0.005 (0.003–0.008) |
| Mixed GCT | 9 (7.4) | 0.007 (0.002–0.012) | 32 (11.1) | 0.008 (0.006–0.012) |
Dash indicates number too small to report. Abbreviation: NOS, not otherwise specified.
a Incidence rates are age specific, not standardized.
b Includes all tumors in site codes C71.5, 71.9, 72.9, and 75.1.