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. Author manuscript; available in PMC: 2012 Aug 22.
Published in final edited form as: J Nucl Med. 2011 Dec 12;53(1):29–36. doi: 10.2967/jnumed.111.092387

TABLE 3.

Cox Regression Analysis of OS and PFS of Predictive Factors

Predictive factor OS
PFS
Univariate
Multivariate
Univariate
Multivariate
P HR P HR P HR P HR
Age 0.939 0.325

No. of recurrences 0.001 2.243 0.645 0.001 2.044 0.267

Baseline KPS 0.06 0.915

Dexamethasone treatment 0.176 0.731

Tumor size change by MRI 0.016 3.220 0.382 0.003 4.151 0.054

Lack of 18F-FLT reduction, 0–2 wk 0.001 5.416 0.795 0.024 2.590 0.264

Lack of 18F-FLT reduction, 0–6 wk <0.001 7.869 <0.001 10.051 0.001 5.225 0.001 5.636

Lack of 18F-FLT increase, 2–6 wk 0.001 5.739 0.674 0.009 3.197 0.833