TABLE 3.
Predictive factor | OS
|
PFS
|
||||||
---|---|---|---|---|---|---|---|---|
Univariate
|
Multivariate
|
Univariate
|
Multivariate
|
|||||
P | HR | P | HR | P | HR | P | HR | |
Age | 0.939 | 0.325 | ||||||
| ||||||||
No. of recurrences | 0.001 | 2.243 | 0.645 | 0.001 | 2.044 | 0.267 | ||
| ||||||||
Baseline KPS | 0.06 | 0.915 | ||||||
| ||||||||
Dexamethasone treatment | 0.176 | 0.731 | ||||||
| ||||||||
Tumor size change by MRI | 0.016 | 3.220 | 0.382 | 0.003 | 4.151 | 0.054 | ||
| ||||||||
Lack of 18F-FLT reduction, 0–2 wk | 0.001 | 5.416 | 0.795 | 0.024 | 2.590 | 0.264 | ||
| ||||||||
Lack of 18F-FLT reduction, 0–6 wk | <0.001 | 7.869 | <0.001 | 10.051 | 0.001 | 5.225 | 0.001 | 5.636 |
| ||||||||
Lack of 18F-FLT increase, 2–6 wk | 0.001 | 5.739 | 0.674 | 0.009 | 3.197 | 0.833 |