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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Immunol. 2012 Jul 30;189(5):2537–2544. doi: 10.4049/jimmunol.1200429

Fig. 4. Reduced activation of Salmonella-specific CD4 T cells by SIRPα-deficient DCs in vitro.

Fig. 4

CD11c+ DCs (1×105) purified from wild type or SIRPα-deficient mice were co-cultured with 1×105 flagellin-specific SM1 T cells in the presence or absence of various dose of antigen flagellin or 10μg/ml flagellin peptide. Graphs depict the percent expression of CD69 (A), CD44 (B), CD25 (C) or loss of CD62L (D) on gated SM1 T cells 16 hours post stimulation. Error bars represent mean ± SEM.