Fig. 5. Salmonella-specific Ab responses in WT and Sirpα−/− mice.
WT and Sirpα−/− mice were infected i.v. with 5 × 105 attenuated Salmonella (BRD509). Serum was collected 2 (A and B) and 3 (C and D) weeks post infection. Salmonella-specific IgM (A and C) and IgG2c (B and D) titer were determined by ELISA. Graphs show OD readings (mean ± SEM) of IgM and IgG2c responses. Data represents three independent experiments with at least four mice per group.