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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Immunol. 2012 Jul 27;189(5):2234–2245. doi: 10.4049/jimmunol.1102606

Fig. 1. Resolution of lung injury is impaired in iNOS−/− mice.

Fig. 1

WT and iNOS−/− mice (n= 8 per group per time point) were challenged with i.t. LPS. Survival (A) and (B) body weight relative to baseline were plotted at intervals after injury. Bronchoalveolar (BAL) protein (C), BAL albumin (D), BAL total cell counts (E) and BAL differential cell counts (F) were determined in WT and iNOS−/− mice after i.t. water (control) or i.t. LPS. (G) Histological sections were stained with H & E in WT and iNOS−/− mice. Original magnifications x20; x100 (insets). (H) Histopathological mean lung injury scores from x20 sections (n=4–6 animals per group per time point). Values expressed as mean ± SEM; *, p<0.05 log-rank test (mortality curves) and unpaired Student’s t test (for other injury parameters).