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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Immunol. 2012 Jul 27;189(5):2234–2245. doi: 10.4049/jimmunol.1102606

Fig. 6. Adoptive transfer of WT monocytes restores resolution of ALI in iNOS−/− mice.

Fig. 6

iNOS−/− mice were challenged with i.t. LPS and 24 hours after injury given PBS (sham) or bone marrow-derived CD11b+ monocytes isolated from iNOS+/+ or iNOS−/− mice by tail vein injection. (A) Survival curves for designated groups (n= 8–10 per group). (B) BAL NOx levels 4 days after i.t. LPS after designated transfers into iNOS−/− mice. Mean ± SEM; *; p<0.05 vs. Compared PBS to iNOS−/−, *#; p<0.05 vs. Compared to WT BM to iNOS−/− (C) Lung H–E sections and (D) histopathological lung injury scoring 10 days after i.t. LPS for designated groups (n=6 per group). (E) BAL protein, (F) BAL total cell counts, (G) BAL neutrophils (as a % of total BAL cells) and (H) BAL TNF-α levels 10 days after i.t. LPS are shown after designated transfers into injured iNOS−/− mice.