Table 1.

Univariable analyses of probability of falling (at least once post-baseline)

Baseline Parameters	Odds Ratio	95% CI	p-value*
Age (yrs)	1.05	(1.02, 1.07)	0.0005
Comorbidity of neurological disorder	3.40	(1.01, 11.41)	0.052**
Comorbidity of depression	1.68	(0.97, 2.91)	0.06
Geriatric DepressionScale score	1.11	(1.02, 1.21)	0.02
UPDRS total	1.07	(1.04, 1.10)	<.0001
PIGD score (average of falling, freezing, walking, PI, gait)	19.54	(6.1,62.6)	<.0001
UPDRS Falling>0	13.40	(5.41,33.2)	<.0001
UPDRS Freezing >0	1.58	(0.30, 8.27)	0.63**
UPDRS Walking>0	1.99	(1.19,3.33)	0.008
UPDRS Gait>0	2.50	(1.54,4.08)	0.0002
PDQ39 Fear of falling (treated as continuous)	1.81	(1.32,2.47)	0.0002
Disease Duration	1.02	(1.00,1.04)	0.064
PDQ-39 Summary score	1.05	(1.03,1.08)	<.0001
Hoehn and Yahr score (treated as continuous)	1.71	(1.07,2.73)	0.026
Gender	0.74	(0.45, 1.20)	0.22
Comorbidity of Musculoskeletal disorders	1.40	(0.85,2.31)	0.183
Comorbidity of Vision disorders	1.46	(0.63, 3.42)	0.38
Polypharmacy (Use of >4 medications)	1.18	(0.72, 1.92)	0.51
Frontal Assessment Battery	0.93	(0.81, 1.07)	0.32

Bolded items have p<0.1 and were included in multiple variable model.

Event rate for post-baseline falls = 20% (n=84).

PIGD: Postural Instability and Gait Disorder

^*Based on Pearson’s Chi-square test (binary outcomes) or likelihood ratio Chi-square test (for continuous and ordinal outcomes).

^**Based on Fisher’s exact test due to sparse cell counts.