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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Mol Carcinog. 2012 Apr 19;53(1):10.1002/mc.21917. doi: 10.1002/mc.21917

Table 3.

List of significant genes carrying miRNA binding site polymorphisms

Case/Control
 No. Times
in bootstrap
sample
miRNA
Binding Site
SNP* 		Tagging
SNP		 Gene Genotype Best
Model‡ 		ww wv vv OR (95%CI)† P
value		 P<0.05
rs13943 rs743409 MAPK1 G/A ADD 261/396 436/734 197/386 0.90
(0.77-0.98)		 0.02 952
rs1063311 rs9607241 MAPK1 T/C ADD 282/541 434/711 178/264 1.14
(1.02-1.29)		 0.03 903
rs12947 rs6773576 CDCP1 G/A ADD 573/1037 281/427 40/52 1.18
(1.01-1.37)		 0.03 848
rs406271 rs406271 TFRC A/G ADD 425/665 389/675 80/176 0.88
(0.77-1.00)		 0.04 662
rs3750505 rs10982724 DEC1 A/G REC 706/1233 173/271 15/12 2.18
(1.01-4.74)		 0.05 514
*

miRNA binding site SNPs and tagging SNPs are within the same haplotype block (r2 > 0.8)

†

Adjusted by age, sex, smoking status.

‡

Best model: the model with smallest P value; ADD: additive model, REC: recessive model.

ww, homozygous wild-type genotype; wv, heterozygous variant genotype; vv, homozygous variant genotype