FIG. 2.

Functional rewiring of the PUF4 posttranscriptional regulon. (A) Enrichment of P4E in each functional category of genes (column) in each fungal species (row). Colors denote the P values for the enrichment of P4E after multiple test correction, as indicated at the bottom. The phylogenetic tree of the studied fungal species is shown to the left. The Saccharomycotina (pink) and Pezizomycotina (light blue) subdivisions are indicated by arrows. Two other fungal clades, Schizosaccharomyces and Basidiomycota, are indicated as dark blue and green, respectively. Yellow lines separate fungal species into four categories based on the evolutionary pattern of the PUF4 posttranscriptional regulon. (B) The average percentage of nucleolar genes with P4E in each group of fungal species.